The Sisson Mine is in the Mother Lode country of California. The mine is in the Tahoe National Forest 8 miles northwest of Sierra City. Access is via the Gold Lake Highway off State Highway 49 east of Sierra City. Follow north on the Gold Lake Highway for 1 mile, turn left on Parker Lake Road and follow it to the end of the road. The OHV trail is a 3-mile hike to the Sisson Mine. The mine is in metasedimentary rocks approximately 3 miles from the contact with intrusive rocks to the east.